Biophysics, Medical Physics and Health Physics
Posted on: 2018-10-17 00:33:31

Prof. Dr. Afia Begum and Dr. Mohammad Abu Sayem Karal are working in this research field. This group is working on the synthesis of lipid vesicles (large unilamellar vesicles – LUVs, giant unilamellar vesicles-GUVs) and observing their static and dynamic functions due to the interaction of nanoparticles, antimicrobial peptides etc. Lipid membranes of vesicles with nano- to micrometer in diameter are basically a closed and spherical structure formed by a double layer of lipid. The vesicles are in center of a huge number of researches which are used as a model of cells, and also for delivering the drug to specific body organs. The group developed irreversible electroporation (IRE) technique for investigating the pore formation or rupture in GUVs with an aim in cancer cell ablation. Micropipette aspiration is another technique for applying the mechanical tension in membranes and observing the rupture of GUVs. This technique is widely used for measuring the elasticity (elastic modulus, bending modulus) of membranes of vesicles/cells. The group also working on the focused impedance method and the nerve conduction velocity measurement under the collaboration of the Department of Biomedical Physics and Technology, University of Dhaka, Bangladesh. Phase contrast fluorescence microscope with DIC mode, fluorescence spectrometer, irreversible electroporation, avanti mini extruder, high speed refrigerated centrifuge, laboratory freezer, incubator and peristaltic pump are using for research in the Biophysics Research Laboratory. Under the collaboration with Bangladesh Atomic Energy Commission, this group conducted research on the radiation dosimetry, environmental radioactivity and radiation protection. This group also investigate the quality control of the machines used in diagnosis and treatment of cancer with radiation.